Anti-SAE1 Polyclonal Antibody - SAlexa Fluor 647
Cat: K006130P - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-SAE1 Polyclonal Antibody - SAlexa Fluor 647 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10055 | 【Swiss Prot】：Q9UBE0 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human SAE1 | |
| 【Public Immunogen Range】：1-346aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).
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