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Anti-Phospho-MAP3K7-S412 Polyclonal Antibody - SAlexa Fluor 532
Cat: K006194P - SAlexa Fluor 532
Summary:
【Product name】:Anti-Phospho-MAP3K7-S412 Polyclonal Antibody - SAlexa Fluor 532 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:6885 【Swiss Prot】:O43318
【Tested applications】:WB
【Recommended dilution】:WB 1:500-1000.
【Immunogen】:A phospho specific peptide corresponding to residues surrounding S412 of human MAP3K7
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
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