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Anti-Phospho-H2AFX-S139 Polyclonal Antibody - SAlexa Fluor 660
Cat: K006207P - SAlexa Fluor 660
Summary:
【Product name】:Anti-Phospho-H2AFX-S139 Polyclonal Antibody - SAlexa Fluor 660 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:3014 【Swiss Prot】:P16104
【Tested applications】:IHC,IF,WB
【Recommended dilution】:WB 1:100-500. IHC 1:50-200. IF 1:100-500.
【Immunogen】:A phospho specific peptide corresponding to residues surrounding S139 of human Histone H2A.x
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Verified picture: