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Anti-CYFIP1 Polyclonal Antibody
Cat: K006303P
Summary:
【Product name】:Anti-CYFIP1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:23191 【Swiss Prot】:Q7L576
【Tested applications】:IP,WB
【Recommended dilution】:WB 1:1000-2000. IP 0.5μg-4μg.
【Immunogen】:Recombinant protein of human CYFIP1
【Public Immunogen Range】:1-270aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
CYFIP1 are cytoplasmic proteins belonging to the CYFIP family. Both proteins bind GTP-bound Rac 1 to release FRM1 in its active state, which is thought to regulate mRNA translation of neural cytoskeletal proteins. A loss of CYFIP1 and CYFIP2 leads to mutant neurons with defective axonal growth and motor function. Also designated specifically Rac1-associated protein 1 (sra-1) or p140sra-1, CYFIP1 contains 1,253 amino acids and is a component of the WAVE2 complex.
Verified picture:
Immunohistochemistry of paraffin-embedded Colorectal cancer(hu) using CYFIP1 antibody at dilution of 1:100 (x100 lens).
Western blot analysis with CYFIP1 antibody diluted at 1:1500;Lane: B cells HepG2 HT-1080 Mouse lung Mouse brain.