Anti-CYFIP1 Polyclonal Antibody - HRP
Cat: K006303P - HRP
Summary:
| 【Product name】：Anti-CYFIP1 Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23191 | 【Swiss Prot】：Q7L576 |
| 【Tested applications】：IP,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：Recombinant protein of human CYFIP1 | |
| 【Public Immunogen Range】：1-270aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
CYFIP1 are cytoplasmic proteins belonging to the CYFIP family. Both proteins bind GTP-bound Rac 1 to release FRM1 in its active state, which is thought to regulate mRNA translation of neural cytoskeletal proteins. A loss of CYFIP1 and CYFIP2 leads to mutant neurons with defective axonal growth and motor function. Also designated specifically Rac1-associated protein 1 (sra-1) or p140sra-1, CYFIP1 contains 1,253 amino acids and is a component of the WAVE2 complex.
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