Anti-JTB Polyclonal Antibody
Cat: K006313P
Summary:
| 【Product name】：Anti-JTB Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10899 | 【Swiss Prot】：O76095 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human JTB | |
| 【Public Immunogen Range】：31-105aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity.
Verified picture:
Immunohistochemistry of paraffin-embedded Liver cancer(hu) using JTB antibody at dilution of 1:100 (x100 lens).
Western blot analysis with JTB antibody diluted at 1:1000;Lane: MCF7 NCI-H460 A375 Rat spleen Rat thymus.