Anti-ITGB5 Polyclonal Antibody - SAlexa Fluor 405
Cat: K006328P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-ITGB5 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3693 | 【Swiss Prot】：P18084 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. | |
| 【Immunogen】：Recombinant protein of human ITGB5 | |
| 【Public Immunogen Range】：490-720aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM.
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