Anti-TRPM8 Polyclonal Antibody
Cat: K006331P
Summary:
| 【Product name】：Anti-TRPM8 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：79054 | 【Swiss Prot】：Q7Z2W7 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TRPM8 | |
| 【Public Immunogen Range】：980-1104aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves.
Verified picture:
Western blot analysis with TRPM8 antibody diluted at 1:1000;Lane: LO2 293T Mouse kidney Mouse heart.