Anti-PRMT2 Polyclonal Antibody
Cat: K006344P
Summary:
| 【Product name】：Anti-PRMT2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3275 | 【Swiss Prot】：P55345 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IF 1:50-100. | |
| 【Immunogen】：Recombinant protein of human PRMT2 | |
| 【Public Immunogen Range】：1-300aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.
Verified picture:
Western blot analysis with PRMT2 antibody diluted at 1:1000;Lane: mouse lung.
Immunohistochemistry of paraffin-embedded human liver injury using PRMT2 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of HeLa cells using PRMT2 antibody.