Anti-CIRBP Polyclonal Antibody
Cat: K006354P
Summary:
| 【Product name】：Anti-CIRBP Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1153 | 【Swiss Prot】：Q14011 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-100. IF 1:10-100. | |
| 【Immunogen】：Recombinant protein of human CIRBP | |
| 【Public Immunogen Range】：1-172aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.
Verified picture:
Western blot analysis with CIRBP antibody diluted at 1:1000;Lane: Jurkat HepG2 U-251MG Mouse brain Mouse testis.
Immunohistochemistry of paraffin-embedded rat testis using CIRBP antibody antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of HeLa cells using CIRBP antibody. Blue: DAPI for nuclear staining.