Anti-PHF19 Polyclonal Antibody - SAlexa Fluor 647
Cat: K006366P - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-PHF19 Polyclonal Antibody - SAlexa Fluor 647 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：26147 | 【Swiss Prot】：Q5T6S3 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human PHF19 | |
| 【Public Immunogen Range】：1-207aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36'(H3K36me3) and recruits the PRC2 complex. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing.
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