Anti-Phospho-EIF4EBP1-T37/46 Polyclonal Antibody - SAlexa Fluor 405
Cat: K006618P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-Phospho-EIF4EBP1-T37/46 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1978 | 【Swiss Prot】：Q13541 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：A phospho specific peptide corresponding to residues surrounding T37/46 of human EIF4EBP1 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes one member of a family of repressor of translation. The protein initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
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