Anti-APPL1 Polyclonal Antibody
Cat: K006675P
Summary:
| 【Product name】：Anti-APPL1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：26060 | 【Swiss Prot】：Q9UKG1 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:10-100. | |
| 【Immunogen】：Recombinant protein of human APPL1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Verified picture:
Western blot analysis with APPL1antibody diluted at 1:1000 ;Lane : Mouse brain
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue with APPL1 antibody diluted at 1:25