Anti-DTX3 Polyclonal Antibody
Cat: K006730P
Summary:
| 【Product name】：Anti-DTX3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：196403 | 【Swiss Prot】：Q8N9I9 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human DTX3 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
DTX3 functions as an E3 ubiquitin ligase. It is regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Verified picture:
Western blot analysis with DTX3 antibody diluted at 1:200;Lane :SKOV3 cells
Immunohistochemistry of paraffin-embedded Human tonsil tissue with DTX3 antibody diluted at 1:20.