Anti-DTX3 Polyclonal Antibody - SAlexa Fluor 660
Cat: K006730P - SAlexa Fluor 660
Summary:
| 【Product name】：Anti-DTX3 Polyclonal Antibody - SAlexa Fluor 660 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：196403 | 【Swiss Prot】：Q8N9I9 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human DTX3 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
DTX3 functions as an E3 ubiquitin ligase. It is regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
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