Anti-GDF15 Polyclonal Antibody
Cat: K006750P
Summary:
| 【Product name】：Anti-GDF15 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9518 | 【Swiss Prot】：Q99988 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-5000. | |
| 【Immunogen】：Recombinant protein of human GDF15 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the emergency circuit that shapes feeding responses to stressful conditions.
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