Anti-GDF15 Polyclonal Antibody - SAlexa Fluor 555
Cat: K006750P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-GDF15 Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9518 | 【Swiss Prot】：Q99988 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human GDF15 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the emergency circuit that shapes feeding responses to stressful conditions.
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