Anti-HCK Polyclonal Antibody
Cat: K006756P
Summary:
| 【Product name】：Anti-HCK Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3055 | 【Swiss Prot】：P08631 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:10-100. | |
| 【Immunogen】：Recombinant protein of human HCK | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Verified picture:
Western blot analysis with HCK antibody diluted at 1:450;Lane: A549
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue with HCK antibody diluted at 1:20