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Anti-HSPH1 Polyclonal Antibody
Cat: K006762P
Summary:
【Product name】:Anti-HSPH1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:10808 【Swiss Prot】:Q92598
【Tested applications】:WB
【Recommended dilution】:WB 1:500-2000.
【Immunogen】:Recombinant protein of human HSPH1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Heat shock protein 105 kDa is a protein that in humans is encoded by the HSPH1 gene. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
Verified picture:
Western blot analysis with HSPH1 antibody diluted at 1:1000;Lane : PC3,Mouse brain,Rat brain