Anti-MUTYH Polyclonal Antibody
Cat: K006797P
Summary:
| 【Product name】：Anti-MUTYH Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4595 | 【Swiss Prot】：Q9UIF7 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:10-100. | |
| 【Immunogen】：Recombinant protein of human MUTYH | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with MUTYH antibody diluted at 1:3000;Lane: Mouse liver,Rat live
Immunohistochemistry of paraffin-embedded Human ovarian cancer with MUTYH antibody diluted at 1:25