Anti-DCT Polyclonal Antibody
Cat: K006848P
Summary:
| 【Product name】：Anti-DCT Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1638 | 【Swiss Prot】：P40126 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:10-100. | |
| 【Immunogen】：Recombinant protein of human DCT | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The human TYRP2 protein has 83% identity and 90% similarity to the mouse sequence and has all the structural characteristics of the tyrosinase protein family, including a signal peptide, 15 conserved cysteine residues, 2 copper-binding domains, and a C-terminal membrane-spanning region. Northern blot analysis showed that TYRP2 is expressed at high levels in human melanoma cells. Its expression is regulated by the microphthalmia-associated transcription factor (MITF).
Verified picture:
Western blot analysis with DCT antibody diluted at 1:1000;Lane: HepG2
Immunohistochemistry of paraffin-embedded Human skin cancer with DCT antibody diluted at 1:25