Anti-DCT Polyclonal Antibody - HRP
Cat: K006848P - HRP
Summary:
| 【Product name】：Anti-DCT Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1638 | 【Swiss Prot】：P40126 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：Recombinant protein of human DCT | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The human TYRP2 protein has 83% identity and 90% similarity to the mouse sequence and has all the structural characteristics of the tyrosinase protein family, including a signal peptide, 15 conserved cysteine residues, 2 copper-binding domains, and a C-terminal membrane-spanning region. Northern blot analysis showed that TYRP2 is expressed at high levels in human melanoma cells. Its expression is regulated by the microphthalmia-associated transcription factor (MITF).
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