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Anti-CNN3 Polyclonal Antibody
Cat: K006866P
Summary:
【Product name】:Anti-CNN3 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1266 【Swiss Prot】:Q15417
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:500-2000. IHC 1:10-100.
【Immunogen】:Recombinant protein of human CNN3
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Verified picture:
Western blot analysis with CNN3 antibody diluted at 1:1000;Lane: Mouse skeletal muscle
Immunohistochemistry of paraffin-embedded Human endometrial cancer with CNN3 antibody diluted at 1:25