Anti-ACVR1C Polyclonal Antibody
Cat: K006871P
Summary:
| 【Product name】：Anti-ACVR1C Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：130399 | 【Swiss Prot】：Q8NER5 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC:1:25-100. | |
| 【Immunogen】：Recombinant protein of human ACVR1C | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).
Verified picture:
Immunohistochemistry of paraffin-embedded Human thyroid cancer with ACVR1C antibody diluted at 1:50