Anti-ADAM17 Polyclonal Antibody
Cat: K006876P
Summary:
| 【Product name】：Anti-ADAM17 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6868 | 【Swiss Prot】：P78536 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:10-50. | |
| 【Immunogen】：Recombinant protein of human ADAM17 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
Verified picture:
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue with NEFL antibody diluted at 1:15