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Anti-AMBRA1 Polyclonal Antibody
Cat: K006898P
Summary:
【Product name】:Anti-AMBRA1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:55626 【Swiss Prot】:Q9C0C7
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:Recombinant protein of human AMBRA1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Human AMBRA1, which encodes a deduced 1,269-amino acid protein. Ambra1 was expressed throughout development in mice, with strong staining in the neuroepithelium. Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3.
Verified picture:
Immunohistochemistry of paraffin-embedded Human brain with AMBRA1 antibody diluted at 1:50