Anti-IKBKG Polyclonal Antibody
Cat: K006910P
Summary:
| 【Product name】：Anti-IKBKG Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8517 | 【Swiss Prot】：Q9Y6K9 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:20-100. | |
| 【Immunogen】：Recombinant protein of human IKBKG | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
Verified picture:
Immunohistochemistry of paraffin-embedded Human endometrial cancer with IKBKG antibody diluted at 1:25