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Anti-UCHL5 Polyclonal Antibody
Cat: K006918P
Summary:
【Product name】:Anti-UCHL5 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:51377 【Swiss Prot】:Q9Y5K5
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:200-1000. IHC 1:20-100.
【Immunogen】:Recombinant protein of human UCHL5
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Ubiquitin carboxyl-terminal hydrolase isozyme L5 is an enzyme that in humans is encoded by the UCHL5gene. Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.
Verified picture:
Western blot analysis with UCHL5 antibody diluted at 1:500; Lane: 293T,MCF7,HT29,HeLa
Immunohistochemistry of paraffin-embedded Human thyroid cancer with UCHL5 antibody diluted at 1:25