Anti-SPTLC1 Polyclonal Antibody
Cat: K006922P
Summary:
| 【Product name】：Anti-SPTLC1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10558 | 【Swiss Prot】：O15269 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:200-1000. | |
| 【Immunogen】：Recombinant protein of human SPTLC1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.
Verified picture:
Western blot analysis with SPTLC1 antibody diluted at 1:500; Lane: SKOV3,MCF7,Mouse lung,Rat lung