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Anti-SIGMAR1 Polyclonal Antibody
Cat: K006923P
Summary:
【Product name】:Anti-SIGMAR1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:10280 【Swiss Prot】:Q99720
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:500-2000. IHC 1:25-200.
【Immunogen】:Recombinant protein of human SIGMAR1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Verified picture:
Western blot analysis with SIGMAR1 antibody diluted at 1:1000; Lane : Mouse liver ,293T,A549,A431,PC-3
Immunohistochemistry of paraffin-embedded Human liver cancer with SIGMAR1 antibody diluted at 1:50