Anti-PLK1 Polyclonal Antibody
Cat: K006931P
Summary:
| 【Product name】：Anti-PLK1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5347 | 【Swiss Prot】：P53350 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1: 25-100 | |
| 【Immunogen】：Recombinant protein of human PLK1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Serine/threonine-protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13 (STPK13), is an enzyme that in humans is encoded by the PLK1 (polo-like kinase 1) gene. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.
Verified picture:
Immunohistochemistry of paraffin-embedded Human liver cancer using PLK1 antibody diluted at 1:20