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Anti-THOC7 Polyclonal Antibody
Cat: K006936P
Summary:
【Product name】:Anti-THOC7 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:80145 【Swiss Prot】:Q6I9Y2
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:500-2000. IHC 1:25-100.
【Immunogen】:Recombinant protein of human THOC7
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
NIF3L1 BP1 (Ngg1-interacting factor 3-like 1 binding protein 1), also known as THOC7 (THO complex subunit 7 homolog), fSAP24 or hTREX30, is a 204 amino acid cytoplasmic and nuclear protein that belongs to the THOC7 family and interacts with NIF3L1. NIF3L1 BP1 is a component of the THO/TREX complex that is recruited to transcribed genes and travels along with RNA polymerase II (Pol II) during elongation, coupling Pol II with RNA splicing and export factors. The THO/TREX complex also plays a role in the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The gene that encodes NIF3L1 BP1 maps to human chromosome 3p14.1.
Verified picture:
Western blot analysis with THOC7 antibody diluted at 1:1000; Lane : Mouse spleen,Mouse testis,A431
Immunohistochemistry of paraffin-embedded Human stomach cancer with THOC7 antibody diluted at 1:30