Anti-SPHK2 Polyclonal Antibody
Cat: K006941P
Summary:
| 【Product name】：Anti-SPHK2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：56848 | 【Swiss Prot】：Q9NRA0 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:20-100. | |
| 【Immunogen】：Recombinant protein of human SPHK2 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with SPHK2 antibody diluted at 1:25