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Anti-ASAH1 Polyclonal Antibody
Cat: K006942P
Summary:
【Product name】:Anti-ASAH1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:427 【Swiss Prot】:Q13510
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:500-2000. IHC 1:20-100.
【Immunogen】:Recombinant protein of human ASAH1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.
Verified picture:
Western blot analysis with ASAH1 antibody diluted at 1:1000; Lane: Human lung cancer tissue
Immunohistochemistry of paraffin-embedded Human breast cancer with ASAH1 antibody diluted at 1:25