Anti-BCAT1 Polyclonal Antibody
Cat: K006957P
Summary:
| 【Product name】：Anti-BCAT1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：586 | 【Swiss Prot】：P54687 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:25-200. | |
| 【Immunogen】：Recombinant protein of human BCAT1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
Verified picture:
Western blot analysis with BCAT1 antibody diluted at 1:1000; Lane: Jurkat,SH-SY5Y,Rat brain
Immunohistochemistry of paraffin-embedded Human breast cancer with BCAT1 antibody diluted at 1:50