Anti-CASC3 Polyclonal Antibody
Cat: K006974P
Summary:
| 【Product name】：Anti-CASC3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：22794 | 【Swiss Prot】：O15234 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:10-100. | |
| 【Immunogen】：Recombinant protein of human CASC3 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the Cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.
Verified picture:
Western blot analysis with CASC3 antibody diluted at 1:1000; Lane: 293T,A549,Jurkat,Mcf7
Immunohistochemistry of paraffin-embedded Human thyroid cancer with CASC3 antibody diluted at 1:20