Anti-PLEKHO1 Polyclonal Antibody
Cat: K006990P
Summary:
| 【Product name】：Anti-PLEKHO1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51177 | 【Swiss Prot】：Q53GL0 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:20-100. | |
| 【Immunogen】：Recombinant protein of human PLEKHO1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Pleckstrin homology domain-containing family O member 1 is a protein that in humans is encoded by thePLEKHO1 gene. Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival.
Verified picture:
Western blot analysis with PLEKHO1 antibody diluted at 1:500; Lane : Hela
Immunohistochemistry of paraffin-embedded Human thyroid cancer with PLEKHO1 antibody diluted at 1:50