Anti-FTO Polyclonal Antibody
Cat: K007043P
Summary:
| 【Product name】：Anti-FTO Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：79068 | 【Swiss Prot】：Q9C0B1 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:10-100. | |
| 【Immunogen】：Recombinant protein of human FTO | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Verified picture:
Western blot analysis with FTO antibody diluted at 1:1000; Lane: 293T,Jurkat
Immunohistochemistry of paraffin-embedded Human thyroid cancer with FTO antibody diluted at 1:30