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Anti-FTO Polyclonal Antibody - SAlexa Fluor 633
Cat: K007043P - SAlexa Fluor 633
Summary:
【Product name】:Anti-FTO Polyclonal Antibody - SAlexa Fluor 633 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:79068 【Swiss Prot】:Q9C0B1
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:500-2000. IHC 1:10-100.
【Immunogen】:Recombinant protein of human FTO
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
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