Anti-HSD17B12 Polyclonal Antibody
Cat: K007064P
Summary:
| 【Product name】：Anti-HSD17B12 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51144 | 【Swiss Prot】：Q53GQ0 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:25-200. | |
| 【Immunogen】：Recombinant protein of human HSD17B12 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.
Verified picture:
Western blot analysis with HSD17B12 antibody diluted at 1:1000; Lane : A549,A431,NIH3T3
Immunohistochemistry of paraffin-embedded Human liver cancer with HSD17B12 antibody diluted at 1:50