Anti-IMPDH2 Polyclonal Antibody
Cat: K007078P
Summary:
| 【Product name】：Anti-IMPDH2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3615 | 【Swiss Prot】：P12268 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:20-200. | |
| 【Immunogen】：Recombinant protein of human IMPDH2 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Verified picture:
Western blot analysis with IMPDH2 antibody diluted at 1:1000; Lane: A549,Mouse testis
Immunohistochemistry of paraffin-embedded Human lung cancer with IMPDH2 antibody diluted at 1:50