Anti-TAB3 Polyclonal Antibody
Cat: K007097P
Summary:
| 【Product name】：Anti-TAB3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：257397 | 【Swiss Prot】：Q8N5C8 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:10-50. | |
| 【Immunogen】：Recombinant protein of human TAB3 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.
Verified picture:
Western blot analysis with TAB3 antibody diluted at 1:800; Lane 1-5: 293T,Raw264.7,NIH3T3,Jurkat
Immunohistochemistry of paraffin-embedded Rat brain with TAB3 antibody diluted at 1:25