Anti-OPTN Polyclonal Antibody - Cy7
Cat: K007148P - Cy7
Summary:
| 【Product name】：Anti-OPTN Polyclonal Antibody - Cy7 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10133 | 【Swiss Prot】：Q96CV9 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:10-100. | |
| 【Immunogen】：Recombinant protein of human OPTN | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.
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