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Anti-PYGL Polyclonal Antibody - SAlexa Fluor 488
Cat: K007154P - SAlexa Fluor 488
Summary:
【Product name】:Anti-PYGL Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5836 【Swiss Prot】:P06737
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human PYGL
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.
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