Anti-SRPX Polyclonal Antibody - SAlexa Fluor 405
Cat: K007178P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-SRPX Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8406 | 【Swiss Prot】：P78539 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:10-100. | |
| 【Immunogen】：Recombinant protein of human SRPX | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
SRPX gene also designated ETX1, resides within this region and is deleted in XLRP patients. There are at least two splice variants of SRPX, one of which contains a thirty amino acid signal peptide. Both variants contain three complement control protein domains, a hydrophobic region for membrane anchorage, and a cytoplasmic carboxy terminus. SRPX is expressed in retina and heart. SRPX is highly homologous to the drs (downregulated by v-src) human homolog, which suggests a role for SRPX as a tumor suppressor.
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