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Anti-VSIG8 Polyclonal Antibody - SAlexa Fluor 633
Cat: K007223P - SAlexa Fluor 633
Summary:
【Product name】:Anti-VSIG8 Polyclonal Antibody - SAlexa Fluor 633 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:391123 【Swiss Prot】:P0DPA2
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:500-2000. IHC 1:200-400.
【Immunogen】:Recombinant protein of human VSIG8
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
VSIG8 (V-set and immunoglobulin domain-containing protein 8), also known as C1orf204, is a 414 amino acid single-pass type I membrane protein that contains two Ig-like V-type (immunoglobulin-like) domains. VSIG8 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 1q23.2. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. The rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia.
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