Anti-ZNF346 Polyclonal Antibody
Cat: K007258P
Summary:
| 【Product name】：Anti-ZNF346 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23567 | 【Swiss Prot】：Q9UL40 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:30-150. | |
| 【Immunogen】：Recombinant protein of human ZNF346 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.
Verified picture:
Western blot analysis with ZNF346 antibody diluted at 1:500; Lane: Human left kidney tissue lysate
Immunohistochemistry of paraffin-embedded Human stomach cancer with ZNF346 antibody diluted at 1:50