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Anti-UMPS Polyclonal Antibody
Cat: K007274P
Summary:
【Product name】:Anti-UMPS Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:7372 【Swiss Prot】:P11172
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:500-2000. IHC 1:25-100.
【Immunogen】:Recombinant protein of human UMPS
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with UMPS antibody diluted at 1:1000; Lane:HT29,HeLa,L-02
Immunohistochemistry of paraffin-embedded Human prostate cancer with UMPS antibody diluted at 1:30