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Anti-SARS spike glycoprotein S1 Polyclonal Antibody - SAlexa Fluor 350
Cat: K009372P - SAlexa Fluor 350
Summary:
【Product name】:Anti-SARS spike glycoprotein S1 Polyclonal Antibody - SAlexa Fluor 350 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Swiss Prot】:P59594
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human SARS glycoprotein S1
【Public Immunogen Range】:101-200/1255aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
S1 attaches the virion to the cell membrane by interacting with human ACE2 and CLEC4M/DC-SIGNR, initiating the infection. Binding to the receptor and internalization of the virus into the endosomes of the host cell probably induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
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