Anti-BMP2 Polyclonal Antibody
Cat: K108262P
Summary:
| 【Product name】：Anti-BMP2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：650 | 【Swiss Prot】：P12643 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of Human BMP2 | |
| 【Public Immunogen Range】：250-300/396aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Induces cartilage and bone formation . Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119; which upregulates the expression of ATF4.
Verified picture:
Western blot analysis with BMP2 antibody diluted at 1:2000;Lane: HUVEC,HeLa,A549,HT29.